Beyond Undetectable: Going the full 360

June 20th–21st, 2019 // Berlin, Germany

Beyond Undetectable: Going the Full 360 brought together HIV specialists from across Europe to discuss and examine best practice in HIV care. The aim of the meeting was to consider progress towards achieving the UNAIDS 90-90-90 goals and set out a framework to move beyond viral-load to achieve the ‘fourth 90’ of life-long good health and wellbeing for people living with HIV (PLHIV).

On this site you can find additional educational materials from the meeting. We hope you find this content informative and impactful in improving care for PLHIV.

 

Speakers

Click on each of the faculty below to find out more
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Prof Dr Jurgen Rockstroch

Professor of Medicine, Head of the HIV Outpatient Clinic

University of Bonn, Germany
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Dr Laura Waters

HIV and Sexual Health Consultant

Mortimer Market Centre, UK
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Dr Lisa Sterman

Associate Clinical Professor of Medicine

University of California, San Francisco, USA
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Dr Jean-Pierre Routy

Professor of Medicine

McGill University, Canada
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Prof Anne-Geneviève Marcelin

Professor of Medicine, Sorbonne University and Clinical Virologist

Pitie-Salpêtrière Hospital, Paris, France
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Mr Ivan Dimov

Founder and Chairman, Single Step Foundation and CEO

Bulgarian Entrepreneurship Center, Bulgaria
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Mr Momchil Baev

Sexual Health Programme Manager

Single Step Foundation, Bulgaria
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Dr Maria Aurora Carleo

Infectious diseases specialist, Unit of immunodeficiency and infectious diseases of gender, "D. Cotugno" Hospital, AO dei Colli

Naples, Italy
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Dr Nesrine Rizk

Assistant Professor of Clinical Medicine

American University of Beirut, Lebanon
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Prof Jeffrey Lazarus

Infectious Disease Policy and Health Systems Expert, Barcelona Institute for Global Health

University of Barcelona, Spain
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Dr Tom Levett

Senior Lecturer in Medicine and Frailty

Brighton and Sussex Medical School, UK
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Dr James Brown

Director, Aston Research Centre for Health Ageing

Aston University, UK
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Prof Richard Harding

Herbert Dunhill Chair

King’s College London, UK
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Dr Cal Cohen

Executive Director of HIV, HIV and HBV Medical Affairs

Gilead Sciences
Prof Dr Jurgen Rockstroch
Professor of Medicine, Head of the HIV Outpatient Clinic
University of Bonn, Germany

Jürgen Rockstroh is a Professor of Medicine and Head of the HIV Outpatient Clinic at the University of Bonn in Germany. He earned a Doctor of Medicine degree from the Rheinische Friedrich-Wilhelms University of Bonn, and there completed his residency in the Department of Medicine. His department treats the world’s largest cohort of HIV-infected haemophiliacs.

In addition to his clinical practice, Dr Rockstroh is involved in HIV research on: antiretroviral therapy, including new drug classes; the course of HIV disease in haemophiliacs; and HIV and hepatitis co-infection. He has been an investigator in multiple clinical trials of antiretroviral agents, as well as treatments for HIV and hepatitis co-infection.

From 2007–2011 he was elected as the president of the German AIDS Society. He is also a member of the executive committee of the European AIDS Clinical Society (EACS) and the governing council of the International AIDS Society since 2009 and 2011 respectively. Dr Rockstroh currently chairs the hepatitis research activities in the European AIDS treatment Network (NEAT) and EuroSIDA, and chaired the National German AIDS Advisory Panel from 2011–2017 and the EACS coinfection guidelines from 2008–2017. In 2015 Dr Rockstroh was elected chair of HIV in Europe, as well as president of EACS in 2019.

The German Society for Infectious Diseases awarded Dr Rockstroh and his co-authors the prize in clinical infectious diseases in 2002, and the national AIDS research prize in 2005. Dr Rockstroh has authored or co-authored over 500 publications in peer-reviewed journals, and over 70 book chapters.

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Dr Laura Waters
HIV and Sexual Health Consultant
Mortimer Market Centre, UK

Laura Waters is a HIV and Sexual Health consultant and HIV and hepatitis lead at Central and North West London NHS Trust’s Mortimer Market Centre. She works predominantly with HIV outpatients. Laura previously worked in clinical trials at Chelsea and Westminster and Brighton, gaining an MD on ART switch and is currently principle or chief investigator on several antiretroviral trials.

She is chair of the British HIV Association (BHIVA) treatment guidelines, previous chair of the BHIVA conferences sub-committee, a BHIVA trustee & honorary secretary; she is also on the British Association of Sexual Health & HIV (BASHH) Board. She is a member of the 2015 & 2019 PEP guidelines writing group and is chairing of the national guidelines for sexual & reproductive health of PLHIV. She is on the HIV Clinical Reference Group (CRG), including the Drugs subgroup, providing advice to NHS England on HIV care.

She has published and presented widely, is a regular columnist for Boyz magazine and is a Terrence Higgins Trust trustee.

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Dr Lisa Sterman
Associate Clinical Professor of Medicine
University of California, San Francisco, USA

Dr Sterman has been in Private Practice, focusing on Internal Medicine and HIV for the past 22 years in San Francisco. She has also been involved in HIV clinical research, and has worked on many registration trials for FDA approved HIV medications since 2000.

She received her MPH from the University of California, Berkley and began working with HIV patients in 1986 while volunteering at San Francisco General Hospital on the AIDS ward. After doing epidemiologic research at the San Francisco’s Veteran Affairs Medical Center in the late 80’s, she went on to attend Medical School at Emory University, where she also carried out HIV research for Emory University Schools of Medicine and Public Health as well as the Centers for Disease Control and Prevention in Atlanta. She completed her residency with an emphasis on HIV/AIDS at the University of California, San Francisco (UCSF) School of Medicine in 1997.

She was one of the landmark founding PrEP providers in San Francisco and continues to be associated with research through UCSF and Quest clinical research exploring the role of inflammation in long-term HIV patients, novel HIV anti-viral mechanisms, and working toward a cure for HIV.

In addition to caring for patients, Dr Sterman is currently involved in education of physicians, students, and community members in the field of HIV medicine. Since 2011, she has served on the Board of Directors for the San Francisco Aids Foundation (SFAF). Over the past 16 years, she has donated countless hours of her time and personally raised over $300,000 through the AIDS Life Cycle, and other charitable events for SFAF.

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Dr Jean-Pierre Routy
Professor of Medicine
McGill University, Canada

Jean-Pierre Routy has dedicated the last two decades to bringing innovation in science and treatment to combatting the health challenges of AIDS and cancer care. He is an attending physician in the Division of Hematology and Chronic Viral Illness Service at the McGill University Health Centre in Montreal Royal, as well as a Professor in the department of Medicine at McGill University. Dr Routy’s fight in health and AIDS related malignancies led to his election as the McGill University Louis Lowenstein Chair in Hematology and Oncology in 2012.

After completing his training in Medicine and Haematology-Oncology at University Aix-Marseille in 1986, he obtained a Postdoctoral Research Fellow Award from the Canadian HIV Trials Network (CTN) and became Assistant Professor in the Department of Medicine at the University of Montreal.

As a Clinician-Scientist, he was able to implement the Montreal Primary HIV-Infection cohort, which generated important findings in HIV pathogenesis and drug resistance transmission. His achievements have led Dr Routy to become the National Co-Director of the Immunotherapy and Vaccine Core at the Canadian Health Research Institutes for the HIV Trials Network. Dr Routy is also a member of the HIV/AIDS Research Advisory Committee for the Federal Government of Canada.

Dr Routy has authored or co-authored over 300 peer-reviewed publications including articles in journals such as: New England Journal of Medicine, The Lancet, Nature Medicine, Blood and AIDS. He also authored a book entitled “What AIDS has changed”, for which he won a literary award from the Ottawa Saint Paul University.

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Prof Anne-Geneviève Marcelin
Professor of Medicine, Sorbonne University and Clinical Virologist
Pitie-Salpêtrière Hospital, Paris, France

Anne-Geneviève Marcelin is a Professor of Medicine at Sorbonne University in Paris and clinical virologist at the Pitié-Salpêtrière Hospital. She is head of a research team dedicated to Therapeutic strategies for HIV infection and associated viral diseases.

Professor Marcelin’s research interests include HIV mechanisms of resistance to antiretrovirals, new therapy strategies for HIV treatment and new antiretroviral agents. She serves as a member of French Agency for Research on AIDS and Viral Hepatitis (ANRS), in the French AC43 Resistance Group and is chair of the ANRS next-generation sequencing network.

Professor Marcelin is also a member of the WHO Steering Group that provides high-level guidance and support in developing and implementing WHO global HIV drug resistance prevention, surveillance and response strategy and is co-chair of the WHO Working Group on Research and Innovation.

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Mr Ivan Dimov
Founder and Chairman, Single Step Foundation and CEO
Bulgarian Entrepreneurship Center, Bulgaria

Ivan Dimov is CEO of the Bulgarian Entrepreneurship Center and Founder and Chairman of the Single Step Foundation which supports, motivates and empowers young LGBTI people in Bulgaria.

His professional career is in the field of finance: as an investment banker and investor in the media, telecommunications and technology sectors in New York, Buenos Aires, Argentina and Sydney, Australia. Mr Dimov is a former CFO of Edamam, which provides nutrition data services and value-added solutions to health, wellness and food businesses. He is also the former Chairman of the Board of Netinfo, the largest internet company in Bulgaria.

Between 2012 and 2014, Mr Dimov served as Treasurer of The Abzyme Research Foundation, a US non-profit organization advancing the creation of an effective therapeutic HIV vaccine.

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Mr Momchil Baev
Sexual Health Programme Manager
Single Step Foundation, Bulgaria

Momchil Baev has 10 years of experience in the field of health as a public health expert, activist and practitioner on various issues including HIV/AIDS. He has been devoted to research, patient access and quality of care. The work he has carried out involves interventions in various fields including infectious and non-communicable diseases and epidemiology. Throughout his professional experience, he has focused on advocacy initiatives related to policy changes, access to healthcare and treatment.

 

Currently, Mr Baev is leading the HIV programme of Single Step Foundation, introducing innovative approaches to improve access to services and care for most-at-risk populations. For five years, he was head of the healthcare department of a large organization coordinating long-term programmes related to access and quality in health. He managed one of the components of the national HIV/AIDS programme, focusing on young people at risk. Later he acted as a programme manager at the largest patients’ association in Bulgaria. He was particularly involved in activities related to patient safety, empowerment and HIV.

HIV/AIDS has been a major part of Mr Baev’s professional qualifications and overall experience. Over the years, he has held a range of responsibilities in the field of HIV including outreach, education and prevention. He worked as an expert during preparation of Ministry of Health’s national HIV/AIDS prevention and control programme, as well as being a member of the expert group on national guidelines for monitoring and treatment of HIV positive adults. He is also a member of the International AIDS Society.

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Dr Maria Aurora Carleo
Infectious diseases specialist, Unit of immunodeficiency and infectious diseases of gender, "D. Cotugno" Hospital, AO dei Colli
Naples, Italy

Dr Carleo is a physician specialising in infectious diseases at the “D. Cotugno” hospital in Naples since 2014. She is a member of the Italian Society of Infectious and Tropical Diseases (SIMIT) and the European Society of Clinical Microbiology and Infectious Diseases (ESCMID), as well as the Regional Group of infectious disease specialists, which aims to educate, collaborate and share experience in order to increase knowledge of general practitioners.

Her primary research interests are: epidemiology and clinical management for PLHIV, including those coinfected with HIV/HCV, drug – drug interactions in HIV patients, antibiotic therapy and clinical management of HBV patients, HCV patients and HCV patients with comorbidities.

Dr Carleo has experience of molecular research in cell differentiation post-exposure to anti-retroviral (ARV) drugs (ovarian cells, bone cells, human hepatic stellate cells). Her current focus is on the latest information and therapeutic approaches for PLHIV, specifically for patients with comorbidities.

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Dr Nesrine Rizk
Assistant Professor of Clinical Medicine
American University of Beirut, Lebanon

Dr Rizk graduated with an MD degree from the American University of Beirut (AUB) in 2001. She completed training in Internal Medicine and then Infectious Diseases at Case Western Reserve University with additional training in HIV/AIDS Medicine.

In 2008, she served as the Medical Director of the HIV programme at the Yale affiliated Cornell Scott-Hill Health Center. She was a member of the Yale AIDS Program.

Dr Rizk joined the medical group practice of the Infectious Diseases Division and the Faculty of Medicine at AUB in 2012, and currently serves as the director of the Antimicrobial Stewardship Program of the AUB Medical Center. Her clinical practice is focused on infectious diseases with a special interest and expertise in HIV and AIDS medicine.

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Prof Jeffrey Lazarus
Infectious Disease Policy and Health Systems Expert, Barcelona Institute for Global Health
University of Barcelona, Spain

Professor Lazarus is an associate research professor at the Barcelona Institute for Global Health (ISGlobal), Hospital Clínic, University of Barcelona.

Currently, he is co-chair of the HIV Outcomes Beyond Viral Suppression coalition, co-founder and steering committee member of EuroTEST (formerly HIV in Europe), vice-chair of the board of the European Association for the Study of the Liver (EASL) International Liver Foundation as well as a scientific adviser for the European Commission’s Joint Actions on infectious diseases (INTEGRATE).

Professor Lazarus is lead co-author of The Lancet HIV series on HIV outcomes beyond viral suppression and a core commissioner of the EASL-Lancet European Liver Commission. He is the author of more than 200 publications and his work on developing a “fourth 90”, addressing quality of life and complementing WHO/UNAIDS targets, has been transformative in the field of HIV.

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Dr Tom Levett
Senior Lecturer in Medicine and Frailty
Brighton and Sussex Medical School, UK

Dr Levett is a Senior Lecturer in medicine and frailty at Brighton and Sussex Medical School and an honorary Consultant Geriatrician in Brighton. He has a special interest in issues of ageing in HIV and has just completed a PhD where he investigated the prevalence and predictors of frailty in older adults with HIV.

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Dr James Brown
Director, Aston Research Centre for Health Ageing
Aston University, UK

Dr Brown is the Director of the Aston Research Centre for Healthy Ageing at Aston University in the UK and a broadcaster with a number of media outlets.

Having graduated with a PhD in 2006 based on the role of fat-secreted hormones in pancreatic function, he has continued to work in the related fields of body fat and how excess body fat affects health and disease including how we age.

Dr Brown’s science communication work includes BBC2’s Trust Me I’m a Doctor, BBC1’s How to Stay Young, BBC1’s Holding Back The Years, ITV1’s ITV Tonight: OAP Bootcamp, BBC1’s The Truth About Obesity, and the BAFTA nominated Channel 4 programme Old Peoples Home for 4 Year Olds.

He is also a Trustee of the British Society for Research on Ageing (BSRA), the oldest biogerontology research society.

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Prof Richard Harding
Herbert Dunhill Chair
King’s College London, UK

Professor Richard Harding is Herbert Dunhill Chair at King’s College London. He has an academic training in social science, social policy and public health.

Professor Harding directs a global health research centre, focused on improving the person-centredness of care for people with serious illness, and on developing, validating and implementing person-centred outcome measures. He leads “POSITIVE OUTCOMES” with UKCAB and BHIV, developing and validating a measure for use in routine HIV care to ensure that assessment, treatment and care are person-centred.

He has also volunteered at HIV NGOs since 1995 in community prevention and care, and now serves as Vice Chair of the World Hospice Palliative Care Alliance.

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Dr Cal Cohen
Executive Director of HIV, HIV and HBV Medical Affairs
Gilead Sciences

Cal Cohen is the Senior Director for HIV and HBV within the Medical Affairs Department at Gilead Sciences.

Before joining Gilead, he was the Director of the Community Research Initiative of New England, Boston, Massachusetts, a Co-Principal Investigator for the New England AIDS Education and Training Center (AETC), and Principal Investigator on numerous clinical trials including the Eviplera trials.

Dr Cohen has received the Upjohn Award for Excellence in Medical Training, the Harvard Pilgrim Health Care Robert H. Ebert Teaching Award, and the Community Recognition Award from the AIDS Action Committee of Massachusetts.

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Agenda

Thursday 20th June
Friday 21st June
13:00
Welcome and introductions

Speakers: Jürgen Rockstroh, Laura Waters, Anne-Geneviève Marcelin, Jeff Lazarus

Going the full 360: Prevention and diagnosis

Co-chair: Jürgen Rockstroh

13:10
Setting new targets and stopping the virus

Speaker: Lisa Sterman

13:35
Inspirations from the clinic

Speaker: Jürgen Rockstroh

14:00
Beyond stigma and discrimination

Speakers: Ivan Dimov and Momchil Baev

14:25
Meet the patients (part 1)

Speakers: Nesrine Rizk and Maria Aurora Carleo

On treatment

Co-chair: Laura Waters

14:50
Linkage to care and treatment

Laura Waters

15:20
Patient cases (part 2)

Nesrine Rizk and Maria Aurora Carleo

15:45
Coffee Break
Viral suppression

Co-chair: Anne-Geneviève Marcelin

16:15
Benefits of optimal viral suppression

Anne-Geneviève Marcelin

16:45
Understanding the role of HIV in inflammation

Jean-Pierre Routy

17:15
Patient cases (part 3)

Nesrine Rizk and Maria Aurora Carleo

17:40
Close
08:30
Welcome and introductions

Speakers: Jürgen Rockstroh, Laura Waters, Anne-Geneviève Marcelin, Jeff Lazarus

Lifelong Good Health

Co-chair: Jeff Lazarus

08:40
On our understanding of aging

James Brown and Tom Levett

09:40
On measures of patient experience and PROs

Richard Harding

10:10
On new targets and tools for achieving lifelong good health

Jeff Lazarus

10:40
Coffee break
11:10
Patient cases (part 4)

Nesrine Rizk and Maria Aurora Carleo

11:40
Beyond Undetectable: Going the full 360

Moderator: Cal Cohen Panel: Jürgen Rockstroh, Laura Waters, AnneGeneviève Marcelin, Jeff Lazarus

12:40
Close

The presentations

Thursday 20th June
Friday 21st June

Going the full 360: Setting new targets and stopping the virus

Going the full 360: Inspirations from the clinic

Going the full 360: Linkage to care and treatment

Going the full 360: Benefits of optimal viral suppression

Going the full 360: on our understanding of ageing

Going the full 360: on measures of patient experience and patient reported outcomes

Going the full 360: on new targets and tools for achieving lifelong good health