Study reveals improvements in renal function following medication switch

Results from a real-world study show reassuring improvements in renal function after switching to elvitegravir/cobicistat/emtricitabine/tenofovir alafenamide (E/C/F/TAF)*1 from E/C/F/tenofovir disoproxil fumarate (E/C/F/TDF) and provide additional clinical evidence that, in comparison to tenofovir disoproxil fumarate (TDF), TAF is associated with significantly less tenofovir (TFV) plasma exposure2,3 and a reduction in off-target effects.4 The findings also concur with guidelines issued by the US Department of Health and Human Services (DHHS).5